123021-85-2
123021-85-2 structure
- Name: Compound 10
- Chemical Name: 2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
- CAS Number: 123021-85-2
- Molecular Formula: C12H9NO5S
- Molecular Weight: 279.26900
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2016-12-07 23:36:51
- Modify Date: 2024-01-05 21:02:23
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GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].
| Name | 2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid |
|---|---|
| Synonyms |
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid GPR35 Agonist,Compound 10 |
| Description | GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 1.4 μM (GPR35)[1]. Ki: 0.0508 μM (GPR35)[1]. IC50: 0.349 μM (GPR35)[1]. |
| In Vitro | GPR35 agonist 3 shows GPR35 agonist potency with an EC50 value of 1.4 μM[1]. GPR35 agonist 3 has affinity and potency for GPR35 with values of 0.0508μM (Ki) and 0.349 μM (IC50)[1]. |
| Molecular Formula | C12H9NO5S |
|---|---|
| Molecular Weight | 279.26900 |
| Exact Mass | 279.02000 |
| PSA | 121.49000 |
| LogP | 1.74980 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |