30368-42-4

30368-42-4 structure

Name: Dalbergioidin
Chemical Name: 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
CAS Number: 30368-42-4
Molecular Formula: C₁₅H₁₂O₆
Molecular Weight: 288.25
Catalog: Natural product Flavonoids
Create Date: 2016-03-08 01:14:24
Modify Date: 2024-01-10 13:35:35
Dalbergioidin, a well-known anthocyanin, ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM[1][2].

Name	3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
Synonyms	darbergioidin dalbergioidine dalbergiodin 4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy- 2',4',5,7-tetrahydroxyisoflavanone 3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one

Description	Dalbergioidin, a well-known anthocyanin, ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM[1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> TGF-beta/Smad Signaling Pathways >> TGF-beta/Smad >> TGF-beta/Smad Research Areas >> Inflammation/Immunology
In Vitro	Dalbergioidin是一种非竞争性抑制剂。此外，DBG在常用作指示生物的海滩链霉菌培养皿中表现出黑色素生物合成的抑制区。
References	[1]. Seunghwa Baek, et al. Inhibitory effect of dalbergioidin isolated from the trunk of Lespedeza cyrtobotrya on melanin biosynthesis. J Microbiol Biotechnol. 2008 May;18(5):874-9. [2]. Xianguo Ren, et al. Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF- β Signal Pathway. Mediators Inflamm. 2016;2016:5147571.

Hazard Codes	Xi