2316-26-9

2316-26-9 structure

Name: 3,4-Dimethoxycinnamic acid
Chemical Name: 3,4-Dimethoxycinnamic acid
CAS Number: 2316-26-9
Molecular Formula: C₁₁H₁₂O₄
Molecular Weight: 208.211
Catalog: Flavors and spices Synthetic spice Aromatic cinnamic acid, esters and derivatives
Create Date: 2018-09-02 10:02:28
Modify Date: 2025-08-22 11:48:03
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1].

Name	3,4-Dimethoxycinnamic acid
Synonyms	RARECHEM BK HC T253 3-(3,4-Dimethoxyphenyl)-2-propenoic Acid 3,4-Dimethoxy cinnamic acid 3,4-Dimethoxycinnamic acid EINECS 219-025-5 3-(3,4-Dimethoxyphenyl)acrylic acid o-Methylferulic acid 3,4-Dimethoxy 3,4-Dimethoxycinnami 2-Propenoic acid, 3-(3,4-dimethoxyphenyl)- DIMETHYLCAFFEIC ACID 2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-, (2E)- 3,4-Dimethoxycinnamic Acid, Predominantly trans 3-(3,4-dimethoxyphenyl)propenoic acid 3,4-Dimethoxycinnamic Acid,Predominantly trans MFCD00004387 Methylferulic acid Donepezil Impurity 33

Description	3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Research Areas >> Cancer Research Areas >> Infection Natural Products >> Phenylpropanoids
In Vitro	3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells[1]. 3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner[1].
References	[1]. Li L, et al. Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signalingpathway. Int J Oncol. 2018 Jul;53(1):225-236.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2916399090

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%