Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Vincamine
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Purity: 98.0%
Stocking Period: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Vincamine
Price: ￥228.0/20mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Vincamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: vincamine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
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Contact: Anson

1617-90-9

1617-90-9 structure

1617-90-9 structure

Name: Vincamine
Chemical Name: vincamine
CAS Number: 1617-90-9
Molecular Formula: C₂₁H₂₆N₂O₃
Molecular Weight: 354.443
Catalog: API Circulatory system medication Peripheral vasodilator
Create Date: 2018-05-17 08:00:00
Modify Date: 2024-01-02 18:40:03
Vincamine is a peripheral vasodilator, that increases blood flow to the brain.

Name	vincamine
Synonyms	EINECS 216-576-3 Methyl (12S,13aS,13bS)-13a-ethyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate vincamine (12S,13aS,13bS)-13a-éthyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij]-1,5-naphtyridine-12-carboxylate de méthyle (3a,14b,16a)-14,15-Dihydro-14-hydroxyeburnamenine-14-carboxylic Acid Methyl Ester Pervone Vraap Methyl-(12S,13aS,13bS)-13a-ethyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij]-1,5-naphthyridin-12-carboxylat Angiopac Perval Equipur MFCD00078054 Vinca Minorin methyl 14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate Monorin Decincan Methyl (3α,14β,16α)-14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate Novicet Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3α,14β,16α)-

Description	Vincamine is a peripheral vasodilator, that increases blood flow to the brain.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease Natural Products >> Alkaloid

Density	1.4±0.1 g/cm3
Boiling Point	508.9±50.0 °C at 760 mmHg
Melting Point	232ºC (dec.)
Molecular Formula	C₂₁H₂₆N₂O₃
Molecular Weight	354.443
Flash Point	261.6±30.1 °C
Exact Mass	354.194336
PSA	54.70000
LogP	3.10
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.682
Storage condition	2~8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YY8575000

CHEMICAL NAME :: Vincamine

CAS REGISTRY NUMBER :: 1617-90-9

LAST UPDATED :: 199706

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C21-H26-N2-O3

MOLECULAR WEIGHT :: 354.49

WISWESSER LINE NOTATION :: T D6 B5666 2AB S CN MN&&TTTJ Q2 SVO1 SQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3852453

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 253 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,601,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 460 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4011330

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0052238

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 47740 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGSOA6 Agressologie. Revue Internationale de Physio-Biologie et de Pharmacologie Appliquees aux Effets de l'Agression. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1960- Volume(issue)/page/year: 19,211,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 236,296,1959

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	YY8575000

Precursor 6
85588-92-7 67-56-1 35226-43-8 61-54-1
14487-98-0 190378-09-7
DownStream 5
4880-88-0 6835-99-0 42971-09-5 3382-95-4
1617-90-9