Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Vinburnine
Price: ￥1958.0/10mg
Purity: 98.0%
Stocking Period: 3 Day
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DC Chemicals Limited
China
Product Name: (-)-Eburnamonine
Price: $550.0/100mg $950.0/250mg $1700.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Henan Tianfu Chemical Co., Ltd.
China
Product Name: (-)-Eburnamonine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

4880-88-0

4880-88-0 structure

4880-88-0 structure

Name: Vinburnine
Chemical Name: (-)-Eburnamonine
CAS Number: 4880-88-0
Molecular Formula: C₁₉H₂₂N₂O
Molecular Weight: 294.391
Catalog: Natural product Alkaloid
Create Date: 2018-08-04 18:19:48
Modify Date: 2024-01-02 20:22:55
Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.

Name	(-)-Eburnamonine
Synonyms	Eburnamenin-14-one, 14,15-dihydro-, (3α,16α)- (13aS,13bS)-13a-éthyl-2,3,6,13,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij]-1,5-naphtyridin-12(5H)-one (3α,16α)-14,15-Dihydroeburnamenin-14-one 3a,16a-Eburnamonine vinburnine (-)-EBURNAMONINE (3a,16a)-Eburnamenin-14(15H)-one (13aS,13bS)-13a-Ethyl-2,3,6,13,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-12(5H)-one Eburnamenin-14(15H)-one, (3α,16α)- Vincamone MFCD00064309 16-Oxoeburnane (3a,16a)-Eburnamin-14(15H)-one EINECS 225-490-5 (13aS,13bS)-13a-Ethyl-2,3,6,13,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij]-1,5-naphthyridin-12(5H)-on cis-Vincamone

Description	Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease

Density	1.3±0.1 g/cm3
Boiling Point	441.9±33.0 °C at 760 mmHg
Melting Point	174-177 °C(lit.)
Molecular Formula	C₁₉H₂₂N₂O
Molecular Weight	294.391
Flash Point	221.0±25.4 °C
Exact Mass	294.173218
PSA	25.24000
LogP	3.79
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.719
Storage condition	-20℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YY8575570

CHEMICAL NAME :: Vincamone

CAS REGISTRY NUMBER :: 4880-88-0

LAST UPDATED :: 199703

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H22-N2-O

MOLECULAR WEIGHT :: 294.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3852453

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 265 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 14,160,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 14,160,1978

Safety Phrases	S22-S24/25
WGK Germany	2
RTECS	YY8575570
HS Code	2933990090

Precursor 7
85588-92-7 111687-22-0 1617-90-9 121074-25-7
393563-08-1 393563-09-2 393563-10-5
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%