- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Mimosine
- Price: ￥888.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: NSC 69188
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1(4H)-Pyridinepropanoicacid, a-amino-3-hydroxy-4-oxo-, (aS)-
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
500-44-7
500-44-7 structure
- Name: Mimosine
- Chemical Name: l-mimosine
- CAS Number: 500-44-7
- Molecular Formula: C8H10N2O4
- Molecular Weight: 198.18
- Catalog: Natural product Alkaloid
- Create Date: 2018-06-06 23:14:32
- Modify Date: 2024-01-02 16:47:32
-
Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity[1]. Mimosine is a known chelator of Fe(III)[2]. Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells[3]. Anti-cancer, antiinflammation.
| Name | l-mimosine |
|---|---|
| Synonyms |
Mimosine
(S)-2-amino-3-(3-hydroxy-4-oxo-4H-[1]pyridyl)-propionic acid EINECS 207-905-1 leucenine (S)-2-Amino-3-(3-hydroxy-4-oxo-4H-[1]pyridyl)-propionsaeure (s)-1(4h)-pyridinepropanoicaci MimosineLeucenol MFCD00075909 L-Mimosine from Koa hoale seeds L-LEUCININE L(-)-MIMOSINE LEUCENOL |
| Description | Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity[1]. Mimosine is a known chelator of Fe(III)[2]. Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells[3]. Anti-cancer, antiinflammation. |
|---|---|
| Related Catalog | |
| In Vitro | Mimosine, a known chelator of Fe(III), may facilitate Fe(III) uptake in leucaena by serving as a phytosiderophore[2]. Mimosine, a bidentate iron-binding ligand, may also play a role in cellular translocation of iron within leucaena[2]. Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumesLeucaenaandMimosa[4]. Mimosine (400 μM), through iron chelation, reversibly blocks cell cycle progression in MDA-MB-453 human breast cancer cells[4]. Mimosine (400 μM) reduces DNA synthesis by greater than 90% of control within 4 hr of treatment, and suppresses total proline-directed protein kinase activity to less than 10% of control after 16 hr treatment[4]. |
| In Vivo | Mimosine (30, and 60 mg/kg) decreases sperm concentration[5]. Animal Model: ICR male mice (6-8 weeks)[5] Dosage: 15, 30, or 60 mg/kg Administration: Injected (i.p.) for 7 consecutive days Result: Could significantly reduce sperm concentration as compared to the control or low dose mimosine group (15 mg/kg) at doses of 30 and 60 mg/kg. |
| References |
| Density | 1.544g/cm3 |
|---|---|
| Boiling Point | 428.6ºC at 760mmHg |
| Melting Point | 224-228 °C |
| Molecular Formula | C8H10N2O4 |
| Molecular Weight | 198.18 |
| Flash Point | 213ºC |
| Exact Mass | 198.06400 |
| PSA | 105.55000 |
| Index of Refraction | 1.645 |
| Storage condition | 2-8C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | R20/21/22 |
| Safety Phrases | S22-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933399090 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |