Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

2997-92-4

2997-92-4 structure

Name: 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Chemical Name: 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
CAS Number: 2997-92-4
Molecular Formula: C₈H₂₀Cl₂N₆
Molecular Weight: 271.191
Catalog: Chemical reagent Organic reagent 肟
Create Date: 2018-11-25 11:12:48
Modify Date: 2026-07-01 23:13:58
AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis[1].

Name	2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Synonyms	2,2'-(Diazene-1,2-diyl)bis(2-MethylpropaniMidaMide) dihydrochloride 2,2'-AZOBIS92-METHYLPROPIONAMIDINE)DIHYDROCHLORIDE 2,2'-Azobis(propane-2-cboxamidine) 2,2'-AZOBIS-(2-AMIDINOPROPANE), 2HCL AAPH Azostarter V 50 2,2'zobis(2-Methylpropionamide)Dihydrochloride 2,2’-azobis(2-methyl-propanimidamiddihydrochloride 2,2'-Azobis(2-methylpropanamidine)·dihydrochloride ABAP 2,2-Azobis(2-Methylpropionamidine) Dihydrochloride ms1(catalyst) v50 alpha,alpha'-Azodiisobutylamidine Dihydrochloride 2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) 2HCl AAPH - - Calbiochem 2,2'-AZOBIS-2-METHYL-PROPANIMIDAMIDE Azobis(isobutyramidine) dihydrochloride 2,2'-AZOBIS(2-AMIDINOPROPANE) DIHYDROCHLORIDE 2,2 -AZOBIS-(2-AMIDINOPROPANE) HCL 1,2-Bis(1-amidino-1-methylethyl)diazene 2,2′-azobis(isobutyramidine) dihydrochloride (E)-2,2'-(diazene-1,2-diyl)bis(2-MethylpropaniMidaMide) dihydrochloride azobis-2-methyl-propanimidamide Azobisisobutyramidinium dichloride 2,2'-AZOBIS-2-METHYL-PROPANIMIDAMIDE, DIHYDROCHLORIDE Azobisisobutylnamide Dihydrochloride 2,2'-AZOBIS(2-METHYLPROPIONAMIDE) DIHYDROCHLORIDE 2,2'-Azobis(2-methylpropionamide) dihydrochloride (V-50) 2,2′-Azobis(2-methylpropionamidine) dihydrochloride,α,α′-Azodiisobutyramidine dihydrochloride, AAPH 2,2'-(e)-diazene-1,2-diylbis(2-methylpropanimidamide) dihydrochloride EINECS 221-070-0 ALPHA,ALPHA'-AZODIISOBUTYRAMIDINE DIHYDROCHLORIDE 2-[2-(1-cbaMiMidoyl-1-Methylethyl)diazen-1-yl]-2-MethylpropaniMidaMide dihydrochloride 2,2'-[(E)-1,2-Diazenediyl]bis(2-methylpropanimidamide) dihydrochloride Azostter V 50 2,2'-Azobis(isobutyramidine) 2HCl Propanimidamide,2,2’-azobis[2-methyl-,dihydrochloride Azobis aminopropane dihydrochloride Propanimidamide, 2,2'-(1,2-diazenediyl)bis[2-methyl-, hydrochloride (1:2) 2,2'-AZOBIS-(2-AMIDOPROPANE) HYDROCHLORIDE 2,2'-AZOBIS-(2-METHYLPROPIONAMIDINE), 2HCL 2,2-AZOBIS-(2-AMIDINOPROPANE) HCL 2,2'-AZOBIS(2-METHYLPROPIONAMIDINE) 2,2- azotwo(2-Methyl propylMi)twohydrochloride ms1 2,2’-azobis(2-methyl-propionamidindihydrochloride 2,2’-azobis[2-methyl-propanimidamiddihydrochloride 2,2μ-Azobis(2-methylpropionamidine) dihydrochloride, AAPH 2,2'-Azobis(2-methylpropionamidine)Dithydrochloride AIBA/V50 2,2'-azobis(2-aminopropane)dihydrochloride 2,2'-Azobis(2-MethylpropionaMidine) dihydrochloride anul 2,2'-AZOBIS(2-METHYLPROPIONAMIDINE) DIHYDROCHLORIDE 2,2'-Azobis(2 AAPH, α,αμ-Azodiisobutyramidine dihydrochloride 2,2'-AZOBIS(ISOBUTYRAMIDINE) DIHYDROCHLORIDE Colesevelam Impurity 9 Propanimidamide, 2,2'-[(E)-1,2-diazenediyl]bis[2-methyl-, hydrochloride (1:2) 2,2‘-Azobis(2-methylpropionamidine) dihydrochloride α,α'-azodiisobutyramidine dihydrochloride 2,2'-azobis(2-methyl-2-propionamidine) dihydrochloride 2,2'-azobisi(2-amidinopropane) hydrochloride 2,2'-Azobis(2-methylpropionamidine) Dihydrochloride 2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride 2,2'-Azobis(2-amidinopropane)·2hydrochloride 2,2-Azobis (2-methylpropionamide) Dihyrochloride propionamidine) dihydrochL 2,2’-Azodiisobutyramidine Dihydrochloride MFCD00142725 2,2'-Azobis-amidinopropane AIBA 2,2'-(3-NITROPHENYLIMINO)-DIETHANOL 2,2'-AzodiisobutyraMidine Dihydrochloride

Description	AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Sean M. Culbertson, et al. Unsymmetrical Azo Initiators Increase Efficiency of Radical Generation in Aqueous Dispersions, Liposomal Membranes, and Lipoproteins. J. Am. Chem. Soc. 2000, 122, 17, 4032–4038. [2]. Liao W, et al. Intracellular antioxidant detoxifying effects of diosmetin on 2,2-azobis(2-amidinopropane) dihydrochloride (AAPH)-induced oxidative stress through inhibition of reactive oxygen species generation. J Agric Food Chem. 2014 Aug 27;62(34):8648-54.

Density	0.42
Boiling Point	267ºC at 760 mmHg
Melting Point	160-169 ºC
Molecular Formula	C₈H₂₀Cl₂N₆
Molecular Weight	271.191
Flash Point	115.3ºC
Exact Mass	270.112640
PSA	124.46000
LogP	4.07180
Vapour Pressure	8.02E-05mmHg at 25°C
Stability	Unstable. Sensitive to heat and light. Incompatible with strong oxidizing agents, strong acids.
Water Solubility	acetone, dioxane, methanol, ethanol, DMSO and water: soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE4575500

CHEMICAL NAME :: Propionamidine, 2,2'-azobis(2-methyl-, dihydrochloride

CAS REGISTRY NUMBER :: 2997-92-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H18-N6.2Cl-H

MOLECULAR WEIGHT :: 271.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0427S ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 410 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0427S

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0427S

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H242-H302-H317
Precautionary Statements	P280
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R43
Safety Phrases	S24-S37
RIDADR	UN 3226 4.1
WGK Germany	1
RTECS	UE4575500
Packaging Group	III
Hazard Class	5.1

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