2997-92-4

2997-92-4 structure

Name: 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Chemical Name: 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
CAS Number: 2997-92-4
Molecular Formula: C₈H₂₀Cl₂N₆
Molecular Weight: 271.191
Catalog: Chemical reagent Organic reagent 肟
Create Date: 2018-11-25 11:12:48
Modify Date: 2025-08-24 11:20:39
AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis[1].

Name	2,2'-Azobis(2-methylpropionamidine) dihydrochloride
Synonyms	2,2-AZOBIS-(2-AMIDINOPROPANE) HCL AAPH Azostarter V 50 ms1 ABAP 2,2-Azobis(2-Methylpropionamidine) Dihydrochloride ms1(catalyst) v50 2,2'-Azobis(2 2,2′-azobis(isobutyramidine) dihydrochloride Propanimidamide, 2,2'-[(E)-1,2-diazenediyl]bis[2-methyl-, hydrochloride (1:2) 2,2‘-Azobis(2-methylpropionamidine) dihydrochloride 2,2'-azobis(2-methyl-2-propionamidine) dihydrochloride 2,2'-azobisi(2-amidinopropane) hydrochloride 2,2'-Azobis(2-methylpropionamidine) Dihydrochloride 2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride 2,2'-(e)-diazene-1,2-diylbis(2-methylpropanimidamide) dihydrochloride EINECS 221-070-0 2,2’-Azodiisobutyramidine Dihydrochloride MFCD00142725 2,2'-[(E)-1,2-Diazenediyl]bis(2-methylpropanimidamide) dihydrochloride 2,2'-Azobis-amidinopropane AIBA 2,2'-(3-NITROPHENYLIMINO)-DIETHANOL 2,2'-Azobis(isobutyramidine) 2HCl

Description	AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Sean M. Culbertson, et al. Unsymmetrical Azo Initiators Increase Efficiency of Radical Generation in Aqueous Dispersions, Liposomal Membranes, and Lipoproteins. J. Am. Chem. Soc. 2000, 122, 17, 4032–4038. [2]. Liao W, et al. Intracellular antioxidant detoxifying effects of diosmetin on 2,2-azobis(2-amidinopropane) dihydrochloride (AAPH)-induced oxidative stress through inhibition of reactive oxygen species generation. J Agric Food Chem. 2014 Aug 27;62(34):8648-54.

Density	0.42
Boiling Point	267ºC at 760 mmHg
Melting Point	160-169 ºC
Molecular Formula	C₈H₂₀Cl₂N₆
Molecular Weight	271.191
Flash Point	115.3ºC
Exact Mass	270.112640
PSA	124.46000
LogP	4.07180
Vapour Pressure	8.02E-05mmHg at 25°C
Stability	Unstable. Sensitive to heat and light. Incompatible with strong oxidizing agents, strong acids.
Water Solubility	acetone, dioxane, methanol, ethanol, DMSO and water: soluble

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0427S ** ACUTE TOXICITY DATA **

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0427S

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0427S