202406-52-8

202406-52-8 structure

Name: L-Leucine-13C6,15N
Chemical Name: L-Leucine (13C6,15N)
CAS Number: 202406-52-8
Molecular Formula: ₁₃C₆H₁₃₁₅NO₂
Molecular Weight: 138.122
Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
Create Date: 2017-08-06 23:51:18
Modify Date: 2024-01-10 11:34:48
L-Leucine-13C6,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

Name	L-Leucine (13C6,15N)
Synonyms	(13C6,15N)Leucine MFCD00144625 Leucine-13C6-15N L-Leucine-13C6,15N L-Leucine-ul-13C,15N L-Isoleucine-13C6,15N 13C and 15N Labeled L-leucine SILAC Amino Acid MFCD00144621 (S)-2-Amino-4-methylpentanoic acid-13C6,15N (2S,3S)-2-Amino-3-methylpentanoic acid-13C6,15N 13C and 15N Labeled L-isoleucine

Description	L-Leucine-13C6,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.