1163133-36-5

1163133-36-5 structure

Name: Fmoc-leucine-13C6,15N
Chemical Name: Fmoc-leucine-13C6,15N
CAS Number: 1163133-36-5
Molecular Formula: C₁₅₁₃C₆H₂₃₁₅NO₄
Molecular Weight: 360.36
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2022-06-29 16:39:05
Modify Date: 2024-02-04 08:30:18
Fmoc-leucine-13C6,15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity

Name	Fmoc-leucine-13C6,15N

Description	Fmoc-leucine-13C6,15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-248. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-248.

Molecular Formula	C₁₅₁₃C₆H₂₃₁₅NO₄
Molecular Weight	360.36