32619-42-4
32619-42-4 structure
- Name: Oleuropein
- Chemical Name: Oleuropein
- CAS Number: 32619-42-4
- Molecular Formula: C25H32O13
- Molecular Weight: 540.514
- Catalog: API Circulatory system medication Antihypertensive drug
- Create Date: 2018-05-17 08:00:00
- Modify Date: 2026-07-01 16:57:54
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Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity[1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase[2].
| Name | Oleuropein |
|---|---|
| Synonyms |
(2S)-3-[(E)-Ethylidene]-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-2H-pyran-4α-acetic acid,[2-(3,4-dihydroxyphenyl)ethyl] ester
Organic Olive Leaf Extract Keywords olive leaf extract A-688 MFCD00017493 (4S,5Z,6R)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-4H-pyran-3-cboxylic acid methyl ester A688 Methyl (3Z)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[3,4,5-trihydroxy-6-(hydroxyMethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-cboxylate Oleuropein Methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-cboxylate Methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-cboxylate Methyl (2S,3E,4S)-4-[2-[2-(3,4-Dihydroxyphenyl)ethoxy]-2-oxoethyl]-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-cboxylate Oleuropein, > Oleuropein //BP oleuropein glucoside Oleuropein (8CI) Oleuropein ext (2S,3E,4S)-3-Ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-2H-pyran-4-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester 2-(3,4-dihydroxyphenyl)ethyl [2S-(2α,3E,4β)]-3-ethylidene Oleuropein, 10 mM in DMSO Olive Leaf Extract 2H-Pyran-4-acetic acid, 3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, [2S-(2alpha,3E,4beta)] 2-(3,4-dihydroxyphenyl)ethyl [2S-(2alpha,3E,4beta)]-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-2H-pyran-4-acetate (2S)-3-[(E)-Ethylidene]-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-2H-pyran-4α-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester Methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-5-carboxylate OLEUROPEIN 2-(3,4-dihydroxyphenyl)ethyl [2S-(2α,3E,4β)]-3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-2H-pyran-4-acetate Oleuropeine glucoside hydroxy complex alcohol EINECS 251-129-6 hydroxy complex alcohol (extract) olive extract Oleuropein 2H-Pyran-4-acetic acid, 3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycbonyl)-, 2-(3,4-dihydroxyphenyl)ethyl ester, (2S,3E,4S) Oleuropein CRS |
| Description | Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity[1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase[2]. |
|---|---|
| Related Catalog | |
| Target |
PPARγ Apoptosis Aromatase |
| In Vitro | Aromatase, a cytochrome P450 enzyme, is an important pharmacological target in breast cancer therapy[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 772.9±60.0 °C at 760 mmHg |
| Melting Point | 89-90ºC |
| Molecular Formula | C25H32O13 |
| Molecular Weight | 540.514 |
| Flash Point | 257.0±26.4 °C |
| Exact Mass | 540.184265 |
| PSA | 201.67000 |
| LogP | -0.91 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.630 |
| Storage condition | room temp |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2938909090 |
| Precursor 0 | |
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| DownStream 2 | |
| HS Code | 2938909090 |
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