CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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KV9360000
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CHEMICAL NAME :
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Ethylene, 1,2-dichloro-
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CAS REGISTRY NUMBER :
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540-59-0
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BEILSTEIN REFERENCE NO. :
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1719345
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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38
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MOLECULAR FORMULA :
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C2-H2-Cl2
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MOLECULAR WEIGHT :
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96.94
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WISWESSER LINE NOTATION :
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G1U1G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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770 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Amphibian - frog
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DOSE/DURATION :
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117 mg/m3/1H
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TOXIC EFFECTS :
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Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression
MUTATION DATA
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TYPE OF TEST :
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DNA damage
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TEST SYSTEM :
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Human Lymphocyte
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REFERENCE :
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MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,185,1996 *** REVIEWS *** ACGIH TLV-TWA 793 mg/m3 (200 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 200 ppm (790 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,80,1971 OSHA PEL (Gen Indu):8H TWA 200 ppm (790 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 200 ppm (790 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 200 ppm (790 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 200 ppm (790 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-BELGIUM:TWA 200 ppm (793 mg/m3) JAN 1993 OEL-DENMARK:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-FINLAND:TWA 200 ppm (790 mg/m3);STEL 250 ppm (990 mg/m3) JAN 1993 OEL-GERMANY:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-HUNGARY:TWA 80 mg/m3;STEL 160 mg/m3 JAN 1993 OEL-JAPAN:TWA 150 ppm (590 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-POLAND:TWA 50 mg/m3 JAN 1993 OEL-RUSSIA:TWA 150 ppm JAN 1993 OEL-SWITZERLAND:TWA 200 ppm (790 mg/m3);STEL 400 ppm JAN 1993 OEL-TURKEY:TWA 200 ppm (790 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 200 ppm (790 mg/m3);STEL 250 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 1,2-DICHLOROETHYLENE-air:10H TWA 200 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 03350 No. of Facilities: 896 (estimated) No. of Industries: 5 No. of Occupations: 6 No. of Employees: 4673 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 03350 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 7 No. of Employees: 216 (estimated) No. of Female Employees: 10 (estimated)
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