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2303-35-7

2303-35-7 structure
2303-35-7 structure
  • Name: (+)-Muscarine (chloride)
  • Chemical Name: (+)-muscarine chloride
  • CAS Number: 2303-35-7
  • Molecular Formula: C9H20ClNO2
  • Molecular Weight: 209.71400
  • Catalog: Signaling Pathways GPCR/G Protein mAChR
  • Create Date: 2018-03-13 23:01:04
  • Modify Date: 2024-01-05 19:13:18
  • Muscarine ((+)-Muscarine) chloride is a toxin that can stimulate the parasympathetic nervous system. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].

Name (+)-muscarine chloride
Synonyms muscarine chloride
muscarine
((2S)-4c-hydroxy-5t-methyl-(2rH)-tetrahydro-furfuryl)-trimethyl-ammonium, chloride
((2S)-4c-Hydroxy-5t-methyl-(2rH)-tetrahydro-furfuryl)-trimethyl-ammonium, Chlorid
Description Muscarine ((+)-Muscarine) chloride is a toxin that can stimulate the parasympathetic nervous system. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].
Related Catalog
In Vitro Muscarine administration (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM ACh[1]. Muscarine (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons[2].
References

[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083.

[2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8.

Molecular Formula C9H20ClNO2
Molecular Weight 209.71400
Exact Mass 209.11800
PSA 29.46000
LogP 1.03290
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300-H310-H330
Precautionary Statements P260-P264-P280-P284-P302 + P350-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
RIDADR UN 2811 6.1 / PGII
RTECS QG3500000
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