(+)-Muscarine (chloride)

Modify Date: 2024-01-05 19:13:18

(+)-Muscarine (chloride) Structure
(+)-Muscarine (chloride) structure
Common Name (+)-Muscarine (chloride)
CAS Number 2303-35-7 Molecular Weight 209.71400
Density N/A Boiling Point N/A
Molecular Formula C9H20ClNO2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of (+)-Muscarine (chloride)


Muscarine ((+)-Muscarine) chloride is a toxin that can stimulate the parasympathetic nervous system. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].

 Names

Name (+)-muscarine chloride
Synonym More Synonyms

 (+)-Muscarine (chloride) Biological Activity

Description Muscarine ((+)-Muscarine) chloride is a toxin that can stimulate the parasympathetic nervous system. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].
Related Catalog
In Vitro Muscarine administration (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM ACh[1]. Muscarine (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons[2].
References

[1]. Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7(1):5083.

[2]. Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14(3 Pt 1):1332-8.

 Chemical & Physical Properties

Molecular Formula C9H20ClNO2
Molecular Weight 209.71400
Exact Mass 209.11800
PSA 29.46000
LogP 1.03290

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300-H310-H330
Precautionary Statements P260-P264-P280-P284-P302 + P350-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
RIDADR UN 2811 6.1 / PGII
RTECS QG3500000

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 Synonyms

muscarine chloride
muscarine
((2S)-4c-hydroxy-5t-methyl-(2rH)-tetrahydro-furfuryl)-trimethyl-ammonium, chloride
((2S)-4c-Hydroxy-5t-methyl-(2rH)-tetrahydro-furfuryl)-trimethyl-ammonium, Chlorid
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