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137525-51-0

137525-51-0 structure
137525-51-0 structure
  • Name: BPC 157
  • Chemical Name: BPC 157
  • CAS Number: 137525-51-0
  • Molecular Formula: C62H98N16O22
  • Molecular Weight: 1419.536
  • Catalog: Biochemical Peptide
  • Create Date: 2018-05-29 15:42:36
  • Modify Date: 2025-08-20 10:39:51
  • BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis[1][2].

Name BPC 157
Synonyms L-Valine, glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-
Bpc 157
Bpc 15
Bpc-157
Glycyl-L-α-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-α-aspartyl-L-α-aspartyl-L-alanylglycyl-L-leucyl-L-valine
L-Valine, glycyl-L-α-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-α-aspartyl-L-α-aspartyl-L-alanylglycyl-L-leucyl-
Booly protection compound 15
Pentadecapeptide
Description BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vivo BPC 157 successfully heals the intestinal anastomosis, gastrocutaneous, duodenocutaneous and colocutaneous fistulas in rats, as well as interacting with the NO-system[1]. BPC 157 (10 μg/kg, 10 ng/kg) is applied either intraperitoneally once time daily (first application immediately after surgery, last at 24 hours before sacrifice) or per-orally in drinking water (0.16 μg/ml/12 ml/day till the sacrifice). A multiple sclerosis suited toxic rat model, cuprizone (compared with standard, a several times higher regimen, 2.5% of diet regimen + 1 g/kg intragastrically/day) was combined with BPC 157 (in drinking water 0.16 μg or 0.16 ng/ml/12 ml/day/rat + 10 μg or 10 ng/kg intragastrically/day) till the sacrifice at day 4. In general, the controls could not heal cysteamine colitis and colon-colon anastomosis. BPC 157 induced an efficient healing of both at the same time[2].
References

[1]. Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17(16):1612-1632.

[2]. Klicek R, et al. Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol. 2013;64(5):597-612.

Density 1.4±0.1 g/cm3
Boiling Point 1802.9±65.0 °C at 760 mmHg
Molecular Formula C62H98N16O22
Molecular Weight 1419.536
Flash Point 1044.2±34.3 °C
Exact Mass 1418.704102
LogP -2.41
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.576
Hazard Codes Xi
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