1702259-66-2

1702259-66-2 structure

Name: H3B-6527
Chemical Name: H3B-6527
CAS Number: 1702259-66-2
Molecular Formula: C₂₉H₃₄Cl₂N₈O₄
Molecular Weight: 629.537
Catalog: Research Areas Cancer
Create Date: 2018-01-17 13:08:45
Modify Date: 2024-01-11 09:53:54
H3B-6527 (H3 Biomedicine) is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.

Name	H3B-6527
Synonyms	2-Propenamide, N-[2-[[6-[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl]methylamino]-4-pyrimidinyl]amino]-5-(4-ethyl-1-piperazinyl)phenyl]- N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}-4-pyrimidinyl)amino]-5-(4-ethyl-1-piperazinyl)phenyl}acrylamide

Description	H3B-6527 (H3 Biomedicine) is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice.
Related Catalog	Research Areas >> Cancer
References	[1]. Dimitra Repana et al. Targeting FGF19/FGFR4 Pathway: A Novel Therapeutic Strategy for Hepatocellular Carcinoma. Diseases 2015, 3, 294-305;