Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ROCK-IN-1
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

934387-35-6

934387-35-6 structure

934387-35-6 structure

Name: ROCK-IN-1
Chemical Name: ROCK-IN-1
CAS Number: 934387-35-6
Molecular Formula: C₂₀H₁₈FN₃O
Molecular Weight: 335.37
Catalog: Signaling Pathways Cell Cycle/DNA Damage ROCK
Create Date: 2018-01-13 00:24:30
Modify Date: 2024-01-08 12:32:14
ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

Name	ROCK-IN-1

Description	ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK Research Areas >> Inflammation/Immunology Research Areas >> Cardiovascular Disease
Target	ROCK2:1.2 nM (IC50)
In Vitro	ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].
References	[1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6.

Molecular Formula	C₂₀H₁₈FN₃O
Molecular Weight	335.37

Hazard Codes	Xi