39537-23-0
39537-23-0 structure
- Name: L-Alanyl-L-Glutamine
- Chemical Name: (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoic acid
- CAS Number: 39537-23-0
- Molecular Formula: C8H15N3O4
- Molecular Weight: 217.22
- Catalog: Biochemical Amino acids and their derivatives Other protected amino acids
- Create Date: 2018-03-07 08:00:00
- Modify Date: 2026-07-02 08:08:38
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L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations[1].
| Name | (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoic acid |
|---|---|
| Synonyms |
Alu-Gln
glutaminic acid L-Alanyl-L-glutamide laevo-alanyl-laevo-glutamine Gln L-alanyl-L-glutamine/alanine diptide/ptide Levoglutamide L-Alanyl-L-glutamine > L-Glutamine,L-alanyl Alanyl glutamine (2S)-2-amino-4-carbamoylbutanoic acid Alanyl-glutamine,Glutamine-S L-Alanyl-L-Glutamine //BP (S)-5-amino-2-((S)-2-aMinopropanaMido)-5-oxopentanoic acid L-ALANY-L-GLUTAMINE Ala-Gln L-Alanyl-L-Glutamin L-Alanyl-L-glutamine(Ala-Gln) 5-Hydroxy-5-imino-L-norvaline N(2)-L-ALANYL-L-GLUTAMINE DIPETIVEN Ala-Glum (L-Alanine-L-glutamine) Ala-Gln|H-Ala-Gln-OH Glycyl-L-Glutamine (Diptiven) L-Glutamic acid γ-amide N-L-alanyl-L-glutamine Alanyl glutamine //BP L-ALANYL-L-GLUTAMINE H-ALA-GLN-OH L-Alanyl-L-Glutamine Alanyl Glutamine L-ALANINE-L-GLUTAMINE Ala-Glum Alanyl-glutaMine(Ala-Gln,GlutaMine-S) l-(+)-glutamic acid-5-amide L-Glutamic acid 5-amide H-Ala-Gln-OH (2S)-5-Amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid MFCD00133046 UNII-U5JDO2770Z Glutamine diptide (2S)-2-((2S)-2-Aminopropanoylamino)-4-carbamoylbutanoic acid ALA-GLN(ALANYL-GLUTAMINE) ZY1&VMYVQ2VZ &&L-L Form L -Alanyl- L -glutamine L-Ala-L-Gln EINECS 475-290-9 Stable Glutamine (L-Alanyl-L-Glutamine Solution), 200 mM glutamine L-Gln Ala-Gln-OH glutamine-s L-Alanyl-L-glutamine Alanyl-glutamine, Glutamine-S (S)-5-Amino-2-[(S)-2-aminopropanamido]-5-oxopentanoic acid Diptamin L-alanine-L-glutamine //BP Aln-Gln Diptiven H-Ala-Gln ALANYL-GLUTAMINE DIPTIVEN (S)-(+)-Glutamine ALANYL-GLUTAMINE CELL CULTURE TESTED N(2)-L-alanyl-L-glutamine N(2)-L-alanyl-L-glutamine //BP Glutamine-S Alanyl-glutamine (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-keto-valeric acid L-Glutamine, L-alanyl L-Glutamic Acid g-Amide L-alanyl-L-glutamine (Glutamine-S) L-Alanyl-L-glutamine, 10 mM in DMSO 200 MM ALA-GLN SOLUTION, BIOTECHNOLOGY PERFORMANCE CERTIFIED STABLE GLUTAMINE Ala-Gln,Alanyl-glutamine, Glutamine-S L-Glutamine l-alanyl-l-glutamin Ala-Gln-OH (HPLC) Diptiven(L-Alanyl-L-Glutamine) ALA-GLN (2S)-5-azanyl-2-[[(2S)-2-azanylpropanoyl]amino]-5-oxo-pentanoic acid Alanyl glutamine Bachem-G1210.0001 Glutamine-X Solution 200mM, Sterile N-L-Alanyl-L-Glutamine Glutamine S(+)-Glutamic acid 5-amide |
| Description | L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations[1]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | L-Alanyl-L-glutamine (2 mM; 24 hours) partially or fully attenuates chronic insulin secretion, and IR-β and COX IV levels which are decreased when β-cells were exposed to macrophages following stimulation in vitro (IMMs)[1]. L-Alanyl-L-glutamine -dependent β-cell protection mediated by coordinated effects on the glutamine-GSH axis, and the HSP pathway, maintenance of mitochondrial metabolism and stimulus-secretion coupling essential for insulin release[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 615℃ |
| Melting Point | 215 °C |
| Molecular Formula | C8H15N3O4 |
| Molecular Weight | 217.22 |
| Flash Point | >110° |
| Exact Mass | 146.069138 |
| PSA | 106.41000 |
| LogP | -1.28 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.564 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S23-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| HS Code | 2924199090 |
|
~64%
39537-23-0 |
| Literature: Zhao, Yufen; Tang, Guo; Zhou, Ning; Hu, Liming; Chen, Yong Patent: US2005/233977 A1, 2005 ; Location in patent: Page/Page column 4-5 ; |
|
~50%
39537-23-0 |
| Literature: Zhao, Yufen; Tang, Guo; Zhou, Ning; Hu, Liming; Chen, Yong Patent: US2005/233977 A1, 2005 ; Location in patent: Page/Page column 4 ; |
|
~%
39537-23-0 |
| Literature: Otsuka Pharmaceutical Co., Ltd. Patent: US4474754 A1, 1984 ; |
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39537-23-0 |
| Literature: Shimonishi,Y. Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 200 - 203 |
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39537-23-0 |
| Literature: Shimonishi,Y. Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 200 - 203 |
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39537-23-0 |
| Literature: Shimonishi,Y. Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 200 - 203 |
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39537-23-0 |
| Literature: Shimonishi,Y. Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 200 - 203 |
|
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39537-23-0 |
| Literature: Shimonishi,Y. Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 200 - 203 |
| Precursor 5 | |
|---|---|
| DownStream 3 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |