Name | Keap1–Nrf2-IN-1 |
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Description | Keap1–Nrf2 IN-1 (compound35) is a Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (Keap1-Nrf2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein. Keap1–Nrf2 IN-1 (compound35) activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models[1]. |
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Related Catalog | |
Target |
IC50: 43 nM (Keap1 protein)[1] |
References |
Molecular Formula | C24H24N2O7S |
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Molecular Weight | 484.52 |