Name | N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide |
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Synonyms |
3-Isoxazolecarboxamide, N-(3-chloro-4-fluorophenyl)-5-(1-methylethyl)-
N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide |
Description | LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice. |
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References | References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. View Related Products by Target SMN2 Modulator |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 327.9±42.0 °C at 760 mmHg |
Molecular Formula | C13H12ClFN2O2 |
Molecular Weight | 282.698 |
Flash Point | 152.1±27.9 °C |
Exact Mass | 282.057129 |
LogP | 3.51 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.582 |