LDN-75654
Modify Date: 2025-09-18 17:43:56
LDN-75654 structure
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Common Name | LDN-75654 | ||
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| CAS Number | 912798-81-3 | Molecular Weight | 282.698 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 327.9±42.0 °C at 760 mmHg | |
| Molecular Formula | C13H12ClFN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 152.1±27.9 °C | |
Use of LDN-75654LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice. |
| Name | N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide |
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| Synonym | More Synonyms |
| Description | LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice. |
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| References | References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. View Related Products by Target SMN2 Modulator |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 327.9±42.0 °C at 760 mmHg |
| Molecular Formula | C13H12ClFN2O2 |
| Molecular Weight | 282.698 |
| Flash Point | 152.1±27.9 °C |
| Exact Mass | 282.057129 |
| LogP | 3.51 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.582 |
| 3-Isoxazolecarboxamide, N-(3-chloro-4-fluorophenyl)-5-(1-methylethyl)- |
| N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide |