1639889-98-7
1639889-98-7 structure
- Name: PDE10A-IN-31
- Chemical Name: PDE10A-IN-31
- CAS Number: 1639889-98-7
- Molecular Formula: C28H23N5O3
- Molecular Weight: 477.524
- Create Date: 2020-01-12 15:01:34
- Modify Date: 2024-01-16 13:00:43
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PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A; dispalys >2,000-fold selective over PDE1B/2A/3B/4D/5A/7A9A, weak activity on CYP isoforms; displays excellent pharmacokinetic properties.
| Name | PDE10A-IN-31 |
|---|
| Description | PDE10A-IN-31 is a potent, highly selective PDE10A inhibitor with IC50 of 2 nM for both rPDE10A and hPDE10A; dispalys >2,000-fold selective over PDE1B/2A/3B/4D/5A/7A9A, weak activity on CYP isoforms; displays excellent pharmacokinetic properties. |
|---|---|
| References | References 1. Meegalla SK, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4216-22. View Related Products by Target Phosphodiesterase (PDE) |
| Molecular Formula | C28H23N5O3 |
|---|---|
| Molecular Weight | 477.524 |