2785430-87-5
2785430-87-5 structure
- Name: ALK5-IN-31
- Chemical Name: ALK5-IN-31
- CAS Number: 2785430-87-5
- Molecular Formula: C23H23FN8
- Molecular Weight: 430.48
- Catalog: Research Areas Cancer
- Create Date: 2022-11-13 15:58:38
- Modify Date: 2024-04-02 13:50:01
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ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].
| Name | ALK5-IN-31 |
|---|
| Description | ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
|---|---|
| Related Catalog | |
| Target |
ALK-5[1]. |
| References |
[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1. |
| Molecular Formula | C23H23FN8 |
|---|---|
| Molecular Weight | 430.48 |