2244904-14-9
2244904-14-9 structure
- Name: BAY-293 racemate
- Chemical Name: BAY-293 racemate
- CAS Number: 2244904-14-9
- Molecular Formula: C25H28N4O2S
- Molecular Weight: 448.585
- Create Date: 2020-01-20 14:55:55
- Modify Date: 2024-01-18 17:32:31
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BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM).
| Name | BAY-293 racemate |
|---|
| Description | BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM). |
|---|---|
| References | References 1. Hillig RC, et al. Proc Natl Acad Sci U S A. 2019 Jan 25. pii: 201812963. doi: 10.1073/pnas.1812963116. View Related Products by Target Ras |
| Molecular Formula | C25H28N4O2S |
|---|---|
| Molecular Weight | 448.585 |