BAY-293 racemate
Modify Date: 2025-09-11 07:11:28
BAY-293 racemate structure
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Common Name | BAY-293 racemate | ||
|---|---|---|---|---|
| CAS Number | 2244904-14-9 | Molecular Weight | 448.585 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H28N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BAY-293 racemateBAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM). |
| Name | BAY-293 racemate |
|---|
| Description | BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM). |
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| References | References 1. Hillig RC, et al. Proc Natl Acad Sci U S A. 2019 Jan 25. pii: 201812963. doi: 10.1073/pnas.1812963116. View Related Products by Target Ras |
| Molecular Formula | C25H28N4O2S |
|---|---|
| Molecular Weight | 448.585 |
| InChIKey | WEGLOYDTDILXDA-UHFFFAOYSA-N |
| SMILES | CNCc1ccccc1-c1csc(C(C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1 |