42588-76-1

42588-76-1 structure

42588-76-1 structure

Name: Hydroxy-PEG2-CH2COONa
Chemical Name: Hydroxy-PEG2-CH2COONa
CAS Number: 42588-76-1
Molecular Formula: C₆H₁₁NaO₅
Molecular Weight: 186.14
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:45:26
Modify Date: 2024-01-09 12:41:11
Hydroxy-PEG2-CH2COONa is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Hydroxy-PEG2-CH2COONa

Description	Hydroxy-PEG2-CH2COONa is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₆H₁₁NaO₅
Molecular Weight	186.14