Shanghai Nianxing Industrial Co., Ltd
China
Product Name: RET-IN-3
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: RET-IN-3
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2414374-53-9

2414374-53-9 structure

2414374-53-9 structure

Name: RET-IN-3
Chemical Name: RET-IN-3
CAS Number: 2414374-53-9
Molecular Formula: C₁₈H₂₁N₅O₂
Molecular Weight: 339.39
Create Date: 2020-08-11 17:57:59
Modify Date: 2024-01-09 15:16:07
RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM[1].

Name	RET-IN-3

Description	RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM[1].
Related Catalog	Research Areas >> Cancer
Target	IC50: 19 nM (RETV804M)[1].
In Vitro	RET-IN-3 exhibits 16 and 410 fold selectivity compared to wt-RET and KDR, respectively[1].
References	[1]. Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505.

Molecular Formula	C₁₈H₂₁N₅O₂
Molecular Weight	339.39

Hazard Codes	Xn