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1949-89-9 6664-99-9
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1949-89-9

1949-89-9 structure
1949-89-9 structure
  • Name: 2-Deoxy-D-lyxo-hexose
  • Chemical Name: 2-deoxy-D-galactose
  • CAS Number: 1949-89-9
  • Molecular Formula: C6H12O5
  • Molecular Weight: 164.156
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-03-08 08:00:00
  • Modify Date: 2025-10-23 12:31:59
  • 2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo[1].
Name 2-deoxy-D-galactose
Synonyms 2-DEOXY-D-LYXOHEXOSE
2-deoxy-galactose
2-deoxy-lyxo-hexose
2-Deoxy-B-D-Lyxo-Hexose
EINECS 217-765-3
Deoxygalactose
2-Dexoy-D-Lyxohexose
D-2-Desoxygalactose
D-2-deoxygalactose
D-lyxo-Hexose, 2-deoxy-
2-Deoxy-D-GalaCLose
D-lyxo-Hexose,2-deoxy
lyxo-Hexose, 2-deoxy-
2-Deoxy-D-Galactopyranose
2-Deoxy-D-galactose
MFCD00014649
DEOXY-D-GALACTOSE,2
2-deoxy-D-talose
(3R,4R,5R)-3,4,5,6-Tetrahydroxyhexanal
Description 2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo[1].
Related Catalog
In Vitro 2-Deoxy-D-galactose (1 mM/L; 5 h) is rapid phosphorylation during the first 30 min and decreases to approximately 20% of this rate during the subsequent hours in ascites hepatoma cells[4].
In Vivo 2-Deoxy-D-galactose (380 mg/kg; i.p.; for 6 times) strongly decreases contents of UMP, UDPG, and UDP galactose in rat livers[1]. 2-Deoxy-D-galactose (2-8 μM; intracerebroventricularly injection; once) shows PAR impairment 30 min before the acquisition trial a dose of 4 μM and 15 min delay after do-gal administration[3]. Animal Model: Male adult Wistar rats with passive avoidance response (PAR) acquisition trial[3] Dosage: 2, 4 and 8 μM Administration: Intracerebroventricularly injection; 2-8 μM; once Result: Exhibited PAR disruption at a dose of 4 μM.
References

[1]. Keppler DO, et al. The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis. Eur J Biochem. 1970 Dec;17(2):246-53.

[2]. Krug M, et al. The amnesic substance 2-deoxy-D-galactose suppresses the maintenance of hippocampal LTP. Brain Res. 1991 Feb 1;540(1-2):237-42.

[3]. Lorenzini CG, et al. 2-Deoxy-D-galactose effects on passive avoidance memorization in the rat. Neurobiol Learn Mem. 1997 Nov;68(3):317-24.

[4]. Smith DF, Keppler DO. 2-Deoxy-D-galactose metabolism in ascites hepatoma cells results in phosphate trapping and glycolysis inhibition. Eur J Biochem. 1977 Feb 15;73(1):83-92.

Density 1.4±0.1 g/cm3
Boiling Point 456.7±45.0 °C at 760 mmHg
Melting Point 107-110 °C(lit.)
Molecular Formula C6H12O5
Molecular Weight 164.156
Flash Point 244.1±25.2 °C
Exact Mass 164.068466
PSA 90.15000
LogP -3.07
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.534
Hazard Codes Xi: Irritant;
Risk Phrases 20/21/22-36/37/38
Safety Phrases S24/25
WGK Germany 3
HS Code 2912491000
73991-08-9 structure

73991-08-9

~84%

1949-89-9 structure

1949-89-9

Literature: Wong, Margaret Y. H.; Gray, Gary R. Carbohydrate Research, 1980 , vol. 80, p. 87 - 98
6207-30-3 structure

6207-30-3

~%

1949-89-9 structure

1949-89-9

Literature: Carbohydrate Research, , vol. 80, p. 87 - 98
73982-55-5 structure

73982-55-5

~%

1949-89-9 structure

1949-89-9

Literature: Carbohydrate Research, , vol. 80, p. 87 - 98
73982-54-4 structure

73982-54-4

~%

1949-89-9 structure

1949-89-9

Literature: Carbohydrate Research, , vol. 80, p. 87 - 98
73982-59-9 structure

73982-59-9

~%

1949-89-9 structure

1949-89-9

Literature: Carbohydrate Research, , vol. 80, p. 87 - 98
HS Code 2912491000
Summary 2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
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