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9004-61-9

9004-61-9 structure
9004-61-9 structure
  • Name: Hyaluronic acid
  • Chemical Name: hyaluronic acid
  • CAS Number: 9004-61-9
  • Molecular Formula: (C14H21NO11)n
  • Molecular Weight: 379.32 (monomer)
  • Catalog: Biochemical Enzymes and coenzymes
  • Create Date: 2018-09-16 18:09:27
  • Modify Date: 2024-01-02 21:45:24
  • Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications.
Name hyaluronic acid
Synonyms (4ξ)-α-D-xylo-hexopyranuronosyl-(1->;3)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1->4)-(5ξ)-β-D-xylo-hexopyranuronosyl-(1->;3)-2-(acetylamino)-2-deoxy-D-glucopyranose
(4ξ)-α-D-xylo-Hexopyranuronosyl-(1->;3)-2-acetamido-2-deoxy-β-D-allopyranosyl-(1->4)-(5ξ)-β-D-xylo-hexopyranuronosyl-(1->3)-2-acetamido-2-deoxy-D-glucopyranose
Hyaluronic Acid Sodium Salt
MFCD00131348
D-Glucopyranose, O(4ξ)-α-D-xylo-hexopyranuronosyl-(1->3)-O-2-(acetylamino)-2-deoxy-β-D-allopyranosyl-(1->4)-O(5ξ)-β-D-xylo-hexopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-
D-glucopyranose, O(4ξ)-α-D-xylo-hexopyranuronosyl-(1->3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1->4)-O(5ξ)-β-D-xylo-hexopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-
EINECS 232-678-0
Description Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Hyaluronic acid (HA) is widely used in aesthetic medicine due to its binding ability with a large number of water molecules. It improves tissue hydration and their resistance to mechanical damage. HA plays an important role in wound healing, ovulation, fertilization, signal transduction, and tumor physiology. HA is used in joint diseases such as osteoarthritis or rheumatoid arthritis. HA of a high molecular mass reduces the chemotaxis and migration of inflammatory cells which acts as a good barrier to the inflammatory process and protects against the effects of free radicals. HA is used in ophthalmology due to its lubricating properties for the corneal endothelium, and improves tissue hydration and cellular resistance to mechanical damage in aesthetic dermatology, and has marginal adverse effects. Several trials indicate its role in tumor markers, liver diseases, and in pharmaceuticals[1]. Hyaluronan plays an important role in cancer growth and metastasis. HA and HA fragment-tumor cell interaction could activate the downstream signaling pathways, promoting cell proliferation, adhesion, migration and invasion, and inducing angiogenesis, lymphangiogenesis, epithelial-mesenchymal transition, stem cell-like property, and chemoradioresistance in digestive cancers[2].
In Vivo The impact of applied intra-articular HA has been proven in many studies in animals. Studies on HA have shown that it promotes the synthesis of cartilage matrix, prevents its degradation, reduces inflammation, stimulates the synthesis of endogenous HA, and improves the resilience and moisture of cartilage [1]. High molecular size HA preparations, applied topically, promote healing of fresh skin wounds. They also promote the healing of venous leg ulcers and are useful in the management of chronic wounds[3].
References

[1]. Salwowska NM, et al. Physiochemical properties and application of hyaluronic acid: a systematic review. J Cosmet Dermatol. 2016 Dec;15(4):520-526.

[2]. Wu RL, et al. Hyaluronic acid in digestive cancers. J Cancer Res Clin Oncol. 2017 Jan;143(1):1-16.

[3]. Kogan G, et al. Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications. Biotechnol Lett. 2007 Jan;29(1):17-25.
Density 1.8±0.1 g/cm3
Boiling Point 1274.4±65.0 °C at 760 mmHg
Molecular Formula (C14H21NO11)n
Molecular Weight 379.32 (monomer)
Flash Point 724.5±34.3 °C
PSA 399.71000
LogP -6.62
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.666
Storage condition −20°C
Water Solubility H2O: 5 mg/mL, clear, colorless | Soluble in water.
Hazard Codes B
Safety Phrases 22-24/25
WGK Germany 3
RTECS MT7250000
HS Code 3004909090
9067-32-7 structure

9067-32-7

~%

9004-61-9 structure

9004-61-9

Literature: US2006/172967 A1, ; Page/Page column 5 ;
Precursor  1

DownStream  1

HS Code 3004909090

Chemsrc provides CAS#:9004-61-9 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 9004-61-9 | Chemsrc address: https://m.chemsrc.com/en/baike/167219.html

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