2738877-91-1

2738877-91-1 structure

Name: Lp-PLA2-IN-4
Chemical Name: Lp-PLA2-IN-4
CAS Number: 2738877-91-1
Molecular Formula: C₂₃H₁₈F₅N₃O₄
Molecular Weight: 495.40
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phospholipase
Create Date: 2022-04-17 09:40:10
Modify Date: 2024-01-10 18:00:11
Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38)[1].

Name	Lp-PLA2-IN-4

Description	Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38)[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
Target	Lp-PLA2[1]
References	[1]. Zhenhua Gu, et al. Bridging cyclic pyrimidinones, methods of preparation thereof, compositions thereof and uses. Patent WO2021228159A1.

Molecular Formula	C₂₃H₁₈F₅N₃O₄
Molecular Weight	495.40