Lp-PLA2-IN-4

Modify Date: 2024-01-10 18:00:11

Lp-PLA2-IN-4 Structure
Lp-PLA2-IN-4 structure
Common Name Lp-PLA2-IN-4
CAS Number 2738877-91-1 Molecular Weight 495.40
Density N/A Boiling Point N/A
Molecular Formula C23H18F5N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lp-PLA2-IN-4


Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38)[1].

 Names

Name Lp-PLA2-IN-4

 Lp-PLA2-IN-4 Biological Activity

Description Lp-PLA2-IN-4 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-4 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2021228159A1, compound 38)[1].
Related Catalog
Target

Lp-PLA2[1]

References

[1]. Zhenhua Gu, et al. Bridging cyclic pyrimidinones, methods of preparation thereof, compositions thereof and uses. Patent WO2021228159A1.

 Chemical & Physical Properties

Molecular Formula C23H18F5N3O4
Molecular Weight 495.40
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