Shanghai Nianxing Industrial Co., Ltd
China
Product Name: EGFR-IN-29
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: EGFR-IN-29
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2682200-93-5

2682200-93-5 structure

2682200-93-5 structure

Name: EGFR-IN-29
Chemical Name: EGFR-IN-29
CAS Number: 2682200-93-5
Molecular Formula: C₃₆H₄₆BrN₈O₂P
Molecular Weight: 733.68
Create Date: 2022-06-21 19:13:13
Modify Date: 2024-01-26 12:59:26
EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].

Name	EGFR-IN-29

Description	EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Research Areas >> Inflammation/Immunology
Target	EGFRT790M
In Vitro	EGFR-IN-29 inhibits Ba/F3 cells with stable overexpression of △19del/T790M/C797S mutant genes, cells overexpressing EGFR WT and A431 carrying EGFR WT with IC50 values of 6.8 nM, 151 nM and 1128 nM, respectively.
References	[1]. Xiangyong Liu. Quinolyl phosphine oxide compound, and composition and application thereof. Patent WO2021160087.

Molecular Formula	C₃₆H₄₆BrN₈O₂P
Molecular Weight	733.68