2254433-37-7
2254433-37-7 structure
- Name: NLRP3-IN-3
- Chemical Name: NLRP3-IN-3
- CAS Number: 2254433-37-7
- Molecular Formula: C22H25N5O3S
- Molecular Weight: 439.534
- Create Date: 2022-07-02 19:07:17
- Modify Date: 2025-08-21 21:12:01
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NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability.
| Name | NLRP3-IN-3 |
|---|
| Description | NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability. |
|---|---|
| References | 1. Sharma R., Iyer P., Agarwal S. Novel Substituted Sulfoximine Compounds. WO/2018/225018. |
| Molecular Formula | C22H25N5O3S |
|---|---|
| Molecular Weight | 439.534 |