NLRP3-IN-3

Modify Date: 2024-01-06 19:20:56

NLRP3-IN-3 Structure
NLRP3-IN-3 structure
Common Name NLRP3-IN-3
CAS Number 2254433-37-7 Molecular Weight 439.534
Density N/A Boiling Point N/A
Molecular Formula C22H25N5O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NLRP3-IN-3


NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability.

 Names

Name NLRP3-IN-3

 NLRP3-IN-3 Biological Activity

Description NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability.
References 1. Sharma R., Iyer P., Agarwal S. Novel Substituted Sulfoximine Compounds. WO/2018/225018.

 Chemical & Physical Properties

Molecular Formula C22H25N5O3S
Molecular Weight 439.534