Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2396664-85-8

2396664-85-8 structure

2396664-85-8 structure

Name: FGFR4-IN-11
Chemical Name: FGFR4-IN-11
CAS Number: 2396664-85-8
Molecular Formula: C₂₉H₂₉N₅O₅
Molecular Weight: 527.57
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
Create Date: 2022-07-29 14:02:27
Modify Date: 2025-08-26 12:47:18
FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].

Name	FGFR4-IN-11

Description	FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR4:2.1 nM (IC50)
References	[1]. Zhong Z, et al. Discovery of Novel 7-Azaindole Derivatives as Selective Covalent Fibroblast Growth Factor Receptor 4 Inhibitors for the Treatment of Hepatocellular Carcinoma. J Med Chem. 2022 May 26;65(10):7278-7295.

Molecular Formula	C₂₉H₂₉N₅O₅
Molecular Weight	527.57

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.