FGFR4-IN-11

Modify Date: 2025-08-26 12:47:18

FGFR4-IN-11 structure	Common Name	FGFR4-IN-11
	CAS Number	2396664-85-8	Molecular Weight	527.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₉N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FGFR4-IN-11

FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].

Name	FGFR4-IN-11

Description	FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR4:2.1 nM (IC50)
References	[1]. Zhong Z, et al. Discovery of Novel 7-Azaindole Derivatives as Selective Covalent Fibroblast Growth Factor Receptor 4 Inhibitors for the Treatment of Hepatocellular Carcinoma. J Med Chem. 2022 May 26;65(10):7278-7295.

Molecular Formula	C₂₉H₂₉N₅O₅
Molecular Weight	527.57

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