2470024-51-0

2470024-51-0 structure
2470024-51-0 structure
  • Name: Apoptosis inducer 8
  • Chemical Name: Apoptosis inducer 8
  • CAS Number: 2470024-51-0
  • Molecular Formula: C29H22ClN5O2
  • Molecular Weight: 507.97
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2022-08-21 00:44:32
  • Modify Date: 2024-04-03 13:04:57
  • Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].

Name Apoptosis inducer 8
Description Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].
Related Catalog
In Vitro Apoptosis inducer 8 (Compound 7c) exhibits an excellent growth inhibition against A-549, NCI-H460, MCF-7 and MDA-MB-23 cells with IC50 values of 0.63 ± 0.21, 0.99 ± 0.01, 1.3 ± 0.18 and 0.94 ± 0.02 µM, respectively[1].
References

[1]. Sridhar Goud N, et al. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg Chem. 2020 Sep;102:104125.

Molecular Formula C29H22ClN5O2
Molecular Weight 507.97