Apoptosis inducer 8

Modify Date: 2024-04-03 13:04:57

Apoptosis inducer 8 Structure
Apoptosis inducer 8 structure
Common Name Apoptosis inducer 8
CAS Number 2470024-51-0 Molecular Weight 507.97
Density N/A Boiling Point N/A
Molecular Formula C29H22ClN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Apoptosis inducer 8


Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].

 Names

Name Apoptosis inducer 8

 Apoptosis inducer 8 Biological Activity

Description Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1].
Related Catalog
In Vitro Apoptosis inducer 8 (Compound 7c) exhibits an excellent growth inhibition against A-549, NCI-H460, MCF-7 and MDA-MB-23 cells with IC50 values of 0.63 ± 0.21, 0.99 ± 0.01, 1.3 ± 0.18 and 0.94 ± 0.02 µM, respectively[1].
References

[1]. Sridhar Goud N, et al. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg Chem. 2020 Sep;102:104125.

 Chemical & Physical Properties

Molecular Formula C29H22ClN5O2
Molecular Weight 507.97
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