188004-07-1

188004-07-1 structure
188004-07-1 structure
  • Name: 2-Deoxy-D-glucose-d1
  • Chemical Name: 2-Deoxy-D-glucose-d1
  • CAS Number: 188004-07-1
  • Molecular Formula: C6H11DO5
  • Molecular Weight: 165.16
  • Catalog: Signaling Pathways Anti-infection HSV
  • Create Date: 2022-10-09 15:53:45
  • Modify Date: 2024-01-29 18:18:30
  • 2-Deoxy-D-glucose-d1 is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

Name 2-Deoxy-D-glucose-d1
Description 2-Deoxy-D-glucose-d1 is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r

Molecular Formula C6H11DO5
Molecular Weight 165.16