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2785430-86-4

2785430-86-4 structure

2785430-86-4 structure

Name: ALK5-IN-30
Chemical Name: ALK5-IN-30
CAS Number: 2785430-86-4
Molecular Formula: C₂₄H₂₅FN₈
Molecular Weight: 444.51
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2022-11-21 12:10:46
Modify Date: 2024-01-10 14:46:08
ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].

Name	ALK5-IN-30

Description	ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
Target	IC50: <10 nM (ALK5)[1]
In Vitro	ALK5-IN-30 (EX-07) exhibits kinase selectivity on ALK5 over ALK2, with selectivity index of ALK2/ALK5 >10[1].
References	[1]. Petermann Oliver, et al. Preparation of carboxymethyl cellulose having improved storage stability: World Intellectual Property Organization, WO2022162133[P]. 2022-08-04.

Molecular Formula	C₂₄H₂₅FN₈
Molecular Weight	444.51

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