ALK5-IN-30

Modify Date: 2024-01-10 14:46:08

ALK5-IN-30 Structure
ALK5-IN-30 structure
Common Name ALK5-IN-30
CAS Number 2785430-86-4 Molecular Weight 444.51
Density N/A Boiling Point N/A
Molecular Formula C24H25FN8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALK5-IN-30


ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].

 Names

Name ALK5-IN-30

 ALK5-IN-30 Biological Activity

Description ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].
Related Catalog
Target

IC50: <10 nM (ALK5)[1]

In Vitro ALK5-IN-30 (EX-07) exhibits kinase selectivity on ALK5 over ALK2, with selectivity index of ALK2/ALK5 >10[1].
References

[1]. Petermann Oliver, et al. Preparation of carboxymethyl cellulose having improved storage stability: World Intellectual Property Organization, WO2022162133[P]. 2022-08-04.

 Chemical & Physical Properties

Molecular Formula C24H25FN8
Molecular Weight 444.51
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