2705900-81-6
2705900-81-6 structure
- Name: ALK5-IN-8
- Chemical Name: ALK5-IN-8
- CAS Number: 2705900-81-6
- Molecular Formula: C19H15FN4O2
- Molecular Weight: 350.35
- Create Date: 2022-06-09 18:35:22
- Modify Date: 2025-08-24 05:17:20
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ALK5-IN-8 is a potent inhibitor of TGFβRI (ALK5). ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)[1].
| Name | ALK5-IN-8 |
|---|
| Description | ALK5-IN-8 is a potent inhibitor of TGFβRI (ALK5). ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)[1]. |
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| Related Catalog | |
| References |
[1]. Zhiyong Yu, et al. Transforming growth factor-beta receptor inhibitor. Patent WO2021190425A1. |
| Molecular Formula | C19H15FN4O2 |
|---|---|
| Molecular Weight | 350.35 |