2651994-75-9
2651994-75-9 structure
- Name: CypD-IN-3
- Chemical Name: CypD-IN-3
- CAS Number: 2651994-75-9
- Molecular Formula: C53H61N7O11
- Molecular Weight: 972.09
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Sirtuin
- Create Date: 2022-11-21 11:28:54
- Modify Date: 2024-07-17 18:58:07
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CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1].
| Name | CypD-IN-3 |
|---|
| Description | CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1]. |
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| Related Catalog | |
| Target |
IC50: 0.01 μM (CypD); 1.1 μM (CypA); 0.21 μM (CypB); 0.31μM (CypE)[1] |
| In Vitro | CypD-IN-3 (B52) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50 values of 0.01 μM, 1.1 μM, 0.21 μM and 0.31 μM, respectively[1]. CypD-IN-3 (10 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1]. |
| Molecular Formula | C53H61N7O11 |
|---|---|
| Molecular Weight | 972.09 |