![]() CypD-IN-3 structure
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Common Name | CypD-IN-3 | ||
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CAS Number | 2651994-75-9 | Molecular Weight | 972.09 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C53H61N7O11 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of CypD-IN-3CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1]. |
Name | CypD-IN-3 |
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Description | CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1]. |
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Related Catalog | |
Target |
IC50: 0.01 μM (CypD); 1.1 μM (CypA); 0.21 μM (CypB); 0.31μM (CypE)[1] |
In Vitro | CypD-IN-3 (B52) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50 values of 0.01 μM, 1.1 μM, 0.21 μM and 0.31 μM, respectively[1]. CypD-IN-3 (10 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1]. |
Molecular Formula | C53H61N7O11 |
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Molecular Weight | 972.09 |