65883-12-7
65883-12-7 structure
- Name: PEG4-Ms
- Chemical Name: 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl methanesulfonate
- CAS Number: 65883-12-7
- Molecular Formula: C9H20O7S
- Molecular Weight: 272.31600
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-12-19 03:26:52
- Modify Date: 2024-01-10 15:21:43
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PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl methanesulfonate |
|---|---|
| Synonyms |
3,6,9,12-Tetraoxa-2-thiatetradecan-14-ol,2,2-dioxide
2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl methanesulfonate 11-[(methylsulfonyl)oxy]-3,6,9-trioxaundecanol |
| Description | PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C9H20O7S |
|---|---|
| Molecular Weight | 272.31600 |
| Exact Mass | 272.09300 |
| PSA | 99.67000 |
| LogP | 0.08550 |
| Precursor 5 | |
|---|---|
| DownStream 8 | |
![2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid structure](https://image.chemsrc.com/caspic/007/172531-37-2.png)
