2115659-62-4

2115659-62-4 structure

Name: R079
Chemical Name: R079
CAS Number: 2115659-62-4
Molecular Formula: C₁₁H₁₁N₃O₃S
Molecular Weight: 265.29
Catalog: Signaling Pathways NF-κB Keap1-Nrf2
Create Date: 2024-03-07 19:15:10
Modify Date: 2024-03-07 19:15:10
R079 (compound 17) is a selective, orally active Nrf2 activator. R079 increases Nrf2 translocation activity (EC50 = 32.41 μM). R079 can neutralize excess levels of reactive oxygen species through activating Nrf2. R079 has anti-inflammatory properties and can be used in multiple sclerosis research [1].

Name	R079

Description	R079 (compound 17) is a selective, orally active Nrf2 activator. R079 increases Nrf2 translocation activity (EC50 = 32.41 μM). R079 can neutralize excess levels of reactive oxygen species through activating Nrf2. R079 has anti-inflammatory properties and can be used in multiple sclerosis research [1].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Simon J. Shaw, et al. Tuning the Reactivity of Nuclear Factor Erythroid 2 Related Factor 2 (Nrf2) Activators for Optimal in Vivo Efficacy. ACS Medicinal Chemistry Letters . 2023，Article ASAP.

Molecular Formula	C₁₁H₁₁N₃O₃S
Molecular Weight	265.29