R079

Modify Date: 2024-03-07 19:15:10

R079 structure	Common Name	R079
	CAS Number	2115659-62-4	Molecular Weight	265.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₁N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of R079

R079 (compound 17) is a selective, orally active Nrf2 activator. R079 increases Nrf2 translocation activity (EC50 = 32.41 μM). R079 can neutralize excess levels of reactive oxygen species through activating Nrf2. R079 has anti-inflammatory properties and can be used in multiple sclerosis research [1].

Name	R079

Description	R079 (compound 17) is a selective, orally active Nrf2 activator. R079 increases Nrf2 translocation activity (EC50 = 32.41 μM). R079 can neutralize excess levels of reactive oxygen species through activating Nrf2. R079 has anti-inflammatory properties and can be used in multiple sclerosis research [1].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Simon J. Shaw, et al. Tuning the Reactivity of Nuclear Factor Erythroid 2 Related Factor 2 (Nrf2) Activators for Optimal in Vivo Efficacy. ACS Medicinal Chemistry Letters . 2023，Article ASAP.

Molecular Formula	C₁₁H₁₁N₃O₃S
Molecular Weight	265.29

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

R079

Use of R079

Names

R079 Biological Activity

Chemical & Physical Properties