88043-21-4
88043-21-4 structure
- Name: BOC-TRANS-4-TOSYLOXY-L-PROLINE METHYL ESTER
- Chemical Name: N-Boc-Trans-4-Tosyloxy-L-Proline Methyl Ester
- CAS Number: 88043-21-4
- Molecular Formula: C18H25NO7S
- Molecular Weight: 399.459
- Catalog: Biochemical Amino acids and their derivatives Proline derivatives
- Create Date: 2018-07-14 20:43:18
- Modify Date: 2026-06-30 11:38:16
| Name | N-Boc-Trans-4-Tosyloxy-L-Proline Methyl Ester |
|---|---|
| Synonyms |
N-TERT-BUTYLOXYCBONYL-O-P-TOLUENESULFONYL-L-PROLINE METHYL ESTER
N-BOC-TRANS-4-TOSYLOXY-L-PROLINE METHYL ESTER N-Boc-(4R)-4-tosyloxy-L-proline methyl ester 1,2-Pyrrolidinedicboxylic acid, 4-[[(4-Methylphenyl)sulfonyl]oxy]-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4R) Zofenopril Calcium Impurity: trans-N-tert-Butyloxycbonyl-4-tosyloxy-L-proline Methyl Ester BOC-trans-4-tosyloxy-L-proline methyl ester:(4R)-4-TsO-N-Boc-Pro-OMe N-Boc-trans-4-(p-tosyloxy)-L-proline methyl ester N-TERT-BUTYLOXYCBONYL-TRANS-4-P-TOLUYLSULFONYLOXY-L-PROLINE METHYL ESTER (2S,trans)-1-tert-Butyl 2-methyl 4-(tosyloxy)pyrrolidine-1,2-dicboxylate 1-tert-butyl 2-methyl (2S,4R)-4-{[(4-methylphenyl)sulfonyl]oxy}pyrrolidine-1,2-dicboxylate Boc-Hyp(Tos)-OMe (2S,4R)-1-tert-butyl 2-methyl 4-(tosyloxy)pyrrolidine-1,2-dicboxylate TRANS-BTPME 2-Methyl 1-(2-methyl-2-propanyl) (2S,4R)-4-{[(4-methylphenyl)sulfonyl]oxy}-1,2-pyrrolidinedicarboxylate 1,2-pyridinedicboxylic acid, 4-(((4-methylphenyl)-sulfonyl(oxyl(-1-(1,1-dimethylethyl)-2-methyl ester, (2S, trans) 1,2-PYRIDINEDICBOXYLIC ACID, 4-[[(4-METHYLPHENYL)-SULFONYL]OXYL]-1-(1,1-DIMETHYLETHYL)-2-METHYL ESTER, (2S, TRANS) N-tert-Butoxycbonyl-O-p-toluenesulfonyl-L-proline methyl ester N-Boc-trans-4-(p-toluenesulfonyloxy)-L-proline Methyl ester 1-O-tert-butyl 2-O-methyl (2S,4R)-4-(4-methylphenyl)sulfonyloxypyrrolidine-1,2-dicarboxylate Boc-trans-4-tosyloxy-L-proline methyl ester (4R)-4-TsO-N-Boc-Pro-OMe trans-N-tert-Butyloxycbonyl-4-tosyloxy-L-proline Methyl Ester (2S,4R)-4-[[(4-Methylphenyl)sulfonyl]oxy]-1,2-pyrrolidinedicboxylic Acid 1-(1,1-DiMethylethyl) 2-Methyl Ester tert-Butyl Methyl (2S,4R)-4-[[(4-Methylphenyl)sulfonyl]oxy]pyrrolidine-1,2-dic N-(tert-Butoxycbonyl)-trans-4-(p-toluenesulfonyloxy)-L-proline Methyl Ester N-Boc-trans-4-tosyloxy-L-proline methyl ester //BP |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 508.1±50.0 °C at 760 mmHg |
| Melting Point | 77.0 to 81.0 °C |
| Molecular Formula | C18H25NO7S |
| Molecular Weight | 399.459 |
| Flash Point | 261.1±30.1 °C |
| Exact Mass | 399.135162 |
| PSA | 107.59000 |
| LogP | 1.77 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.554 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
|
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| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 24 p. 6107 - 6111 |
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| Literature: EP1308439 A1, ; |
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| Literature: Angewandte Chemie - International Edition, , vol. 52, # 36 p. 9539 - 9543 Angew. Chem., , vol. 125, # 36 p. 9718 - 9722 |
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| Literature: US2013/115194 A1, ; |
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| Literature: US2013/115194 A1, ; |
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| Literature: Angewandte Chemie - International Edition, , vol. 52, # 36 p. 9539 - 9543 Angew. Chem., , vol. 125, # 36 p. 9718 - 9722 |
| Precursor 5 | |
|---|---|
| DownStream 4 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |