PROTAC Linker 17

Modify Date: 2024-01-15 11:56:35

PROTAC Linker 17 structure	Common Name	PROTAC Linker 17
	CAS Number	189209-27-6	Molecular Weight	380.47700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₃₆N₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC Linker 17

PROTAC Linker 17 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 17 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonym	More Synonyms

Description	PROTAC Linker 17 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 17 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₇H₃₆N₂O₇
Molecular Weight	380.47700
Exact Mass	380.25200
PSA	113.99000
LogP	1.45750

Hazard Codes	Xi

t-boc-N-amido-P...

CAS#:911209-07-9

~99%

PROTAC Linker 17

CAS#:189209-27-6

Literature: Gerard, Estelle; Meulle, Aline; Feron, Olivier; Marchand-Brynaert, Jacqueline Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 586 - 590

N-Boc-PEG6-alcohol

CAS#:331242-61-6

PROTAC Linker 17

CAS#:189209-27-6