139115-92-7

139115-92-7 structure

Name: tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate
Chemical Name: 2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethanol
CAS Number: 139115-92-7
Molecular Formula: C₁₁H₂₃NO₅
Molecular Weight: 249.30400
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-01-04 14:45:15
Modify Date: 2024-01-02 12:39:03
PROTAC Linker 10 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 10 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethanol
Synonyms	tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate tert-butyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate

Description	PROTAC Linker 10 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 10 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Hazard Codes	Xi
HS Code	2924199090

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%