60820-94-2

60820-94-2 structure

Name: Esculentoside B
Chemical Name: Phytolaccoside B
CAS Number: 60820-94-2
Molecular Formula: C₃₆H₅₆O₁₁
Molecular Weight: 664.82
Catalog: Natural product Moss
Create Date: 2017-05-13 04:01:16
Modify Date: 2024-01-03 00:19:20
Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].

Name	Phytolaccoside B
Synonyms	EsculentosideB (2β,3β)-2,23-Dihydroxy-30-methoxy-30-oxo-3-(β-D-xylopyranosyloxy)olean-12-en-28-oic acid Olean-12-ene-28,30-dioic acid, 2,23-dihydroxy-3-(β-D-xylopyranosyloxy)-, 30-methyl ester, (2β,3β)-

Description	Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> MAPK/ERK Pathway >> JNK Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Abekura F, et al. Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells. Int Immunopharmacol. 2019;68:156-163. [2]. Ren S, et al. Metabolic exploration of the developmental abnormalities and neurotoxicity of Esculentoside B, the main toxic factor in Phytolaccae radix. Food Chem Toxicol. 2023;176:113777. [3]. Escalante A, et al. Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. J Nat Prod. 2008;71(10):1720-1725.

Hazard Codes	Xi